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KMID : 0359720210390020082
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Journal of the Korean Neurological Association
2021 Volume.39 No. 2 p.82 ~ p.84
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Subacute Combined Degeneration with Motor Neuropathy Following Nitrous Oxide Abuse
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Bae Jin-Sung
Seok Jung-Im
Lee Je-Wan
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Abstract
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The neurotoxicity of nitrous oxide (N2O) is known to be mainly occurred by interference with action of vitamin B12. A 38-year-old male presented with progressive gait instability after recreational inhalational use of N2O for 2 months. Although spine magnetic resonance image showed typical subacute combined degeneration, nerve conduction study showed motor neuropathy that is atypical findings of vitamin B12 deficiency. This case suggests N2O-induced neuropathy can develop separately from a vitamin B12 deficiency.
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KEYWORD
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Nitrous oxide, Peripheral nervous system diseases, Subacute combined degeneration
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